Systematic detection of epistatic interactions based on allele pair frequencies

ImAP is a method to detect epistatic interactions based on the frequency of allele pairs in a population.The rationale is that incompatible alleles will occur less frequently than expected in a population.

ImAP exploits the known family structure (parent-child trios) in order to improve the statistical power.

Publication:

Data: HS_genotypes.zip (see the readme-file inside)
R-code: ImAP-Rcode.zip