Genome Generator

The genomeGenerator is a Python tool generating individual-specific genome sequence (.fasta) and annotation (.GFF) files from a reference genome sequence (.fasta), annotation (.GFF) and a the individuals’ genetic variation information (.VCF). It currently only works for haploid organisms.

Genome Generator package: (version 1.0)

See link bellow for more details:

Nature genetic variation impacts expression levels of coding, non-coding, and antisense transcripts in fission yeast.