We have created two methods for the integrative analysis of high-dimensional functional genomics data (such as RNAi screens). The first one uses predefined sets of related genes to identify sets enriched for particular phenotypic signatures. The second is based on network information and extracts sub-networks with consistent phenotypes.
The manuscript is currently under review. Here you can download the input data. The MATLAB source code is available on GitHub.
Documentation & Data
Documentation_IMPACT.20140304.pdf (491 KB) Input Files.zip (25.4 MB)
Code
Source code (on GitHub)